Session Type: 1,5-hour Oral Session
Session Title: 1,5-hour Oral Session
Authors(s): C. Makarenko (1), A. San Pedro (2), N. Paiva (1), R. Medronho (1), G. Gibson (1)
Authors Affiliations(s): (1) Instituto de Estudos em Saúde Coletiva, Universidade Federal do Rio de Janeiro -UFRJ, Brazil, (2) Grupo de Análise Territorial em Saúde - GATES, Brazil
Background:
Although it was declared as having been eliminated from the Americas in 2016, measles has again become a public health concern in several Latin American countries. In Brazil, the most populous state in the country, São Paulo State (SPS), faced a massive outbreak in 2019, that began with imported cases from Europe and Israel. This study aims to analyze the clinical-epidemiological profile of confirmed measles cases in SPS and analyze spatial and temporal distribution during the 2019 epidemic.
Methods:A cross-sectional study was carried out based on confirmed measles cases in SPS. The cases were described according to socioeconomic, epidemiological, and clinical variables and stratified by vaccination status and hospitalization. Incidence rates per municipality were stabilized by Local Empirical Bayes methods before mapping.
Results:There were 15,607 confirmed cases of measles in SPS in 2019, of which 2,039 were hospitalized and 17 resulted in death. After the first confirmed case on Epidemiological Week (EW) 6, the epidemic peak was reached on EW 33, when 1,446 cases were confirmed. Most cases were men (52.1%), between 18 and 29 years old (39.7%). Among those who were 18 and older, the majority had at least 9 years of formal schooling (56.1%). Around 70.0% have self-declared as being white. The main clinical manifestation, beside fever and rash, were cough (76.1%), coryza (62.7%) and conjunctivitis (33.0%). On a bivariate analysis, we observed higher prevalence of vaccination in the group younger than 29 years of age. Self-declared black and brown patients had a lower vaccination prevalence in comparison with white patients (PR= 0.83; CI95%=0.74,0.95; PR=0.83, CI95%=0.79,0.87). Similarly, we observed lower prevalences of vaccination in groups with less years of schooling when compared to those with 13 years or more (PR = 0.72, 95% CI95% = 0.63,0.82). Regarding hospitalization, children younger than 1 year old had a higher prevalence compared to older age groups. Spatial analysis showed a main cluster in the metropolitan area characterized by higher incidence rates.
Conclusions:The findings show a high number of vaccinated individuals among cases, which suggest an incomplete vaccination schedule, and children younger than one year old as more susceptible for hospitalization.
Keyword(s): Measles, Re-emergence, EpidemiologyCOI Other: The authors declare no conflict of interest
Session Type: 1,5-hour Oral Session
Session Title: 1,5-hour Oral Session
Authors(s): C. Makarenko (1), A. San Pedro (2), N. Paiva (1), R. Medronho (1), G. Gibson (1)
Authors Affiliations(s): (1) Instituto de Estudos em Saúde Coletiva, Universidade Federal do Rio de Janeiro -UFRJ, Brazil, (2) Grupo de Análise Territorial em Saúde - GATES, Brazil
Background:
Although it was declared as having been eliminated from the Americas in 2016, measles has again become a public health concern in several Latin American countries. In Brazil, the most populous state in the country, São Paulo State (SPS), faced a massive outbreak in 2019, that began with imported cases from Europe and Israel. This study aims to analyze the clinical-epidemiological profile of confirmed measles cases in SPS and analyze spatial and temporal distribution during the 2019 epidemic.
Methods:A cross-sectional study was carried out based on confirmed measles cases in SPS. The cases were described according to socioeconomic, epidemiological, and clinical variables and stratified by vaccination status and hospitalization. Incidence rates per municipality were stabilized by Local Empirical Bayes methods before mapping.
Results:There were 15,607 confirmed cases of measles in SPS in 2019, of which 2,039 were hospitalized and 17 resulted in death. After the first confirmed case on Epidemiological Week (EW) 6, the epidemic peak was reached on EW 33, when 1,446 cases were confirmed. Most cases were men (52.1%), between 18 and 29 years old (39.7%). Among those who were 18 and older, the majority had at least 9 years of formal schooling (56.1%). Around 70.0% have self-declared as being white. The main clinical manifestation, beside fever and rash, were cough (76.1%), coryza (62.7%) and conjunctivitis (33.0%). On a bivariate analysis, we observed higher prevalence of vaccination in the group younger than 29 years of age. Self-declared black and brown patients had a lower vaccination prevalence in comparison with white patients (PR= 0.83; CI95%=0.74,0.95; PR=0.83, CI95%=0.79,0.87). Similarly, we observed lower prevalences of vaccination in groups with less years of schooling when compared to those with 13 years or more (PR = 0.72, 95% CI95% = 0.63,0.82). Regarding hospitalization, children younger than 1 year old had a higher prevalence compared to older age groups. Spatial analysis showed a main cluster in the metropolitan area characterized by higher incidence rates.
Conclusions:The findings show a high number of vaccinated individuals among cases, which suggest an incomplete vaccination schedule, and children younger than one year old as more susceptible for hospitalization.
Keyword(s): Measles, Re-emergence, EpidemiologyCOI Other: The authors declare no conflict of interest
Session Type: 1,5-hour Oral Session
Session Title: 1,5-hour Oral Session
Authors(s): C. Makarenko (1), A. San Pedro (2), N. Paiva (1), R. Medronho (1), G. Gibson (1)
Authors Affiliations(s): (1) Instituto de Estudos em Saúde Coletiva, Universidade Federal do Rio de Janeiro -UFRJ, Brazil, (2) Grupo de Análise Territorial em Saúde - GATES, Brazil
Background:
Although it was declared as having been eliminated from the Americas in 2016, measles has again become a public health concern in several Latin American countries. In Brazil, the most populous state in the country, São Paulo State (SPS), faced a massive outbreak in 2019, that began with imported cases from Europe and Israel. This study aims to analyze the clinical-epidemiological profile of confirmed measles cases in SPS and analyze spatial and temporal distribution during the 2019 epidemic.
Methods:A cross-sectional study was carried out based on confirmed measles cases in SPS. The cases were described according to socioeconomic, epidemiological, and clinical variables and stratified by vaccination status and hospitalization. Incidence rates per municipality were stabilized by Local Empirical Bayes methods before mapping.
Results:There were 15,607 confirmed cases of measles in SPS in 2019, of which 2,039 were hospitalized and 17 resulted in death. After the first confirmed case on Epidemiological Week (EW) 6, the epidemic peak was reached on EW 33, when 1,446 cases were confirmed. Most cases were men (52.1%), between 18 and 29 years old (39.7%). Among those who were 18 and older, the majority had at least 9 years of formal schooling (56.1%). Around 70.0% have self-declared as being white. The main clinical manifestation, beside fever and rash, were cough (76.1%), coryza (62.7%) and conjunctivitis (33.0%). On a bivariate analysis, we observed higher prevalence of vaccination in the group younger than 29 years of age. Self-declared black and brown patients had a lower vaccination prevalence in comparison with white patients (PR= 0.83; CI95%=0.74,0.95; PR=0.83, CI95%=0.79,0.87). Similarly, we observed lower prevalences of vaccination in groups with less years of schooling when compared to those with 13 years or more (PR = 0.72, 95% CI95% = 0.63,0.82). Regarding hospitalization, children younger than 1 year old had a higher prevalence compared to older age groups. Spatial analysis showed a main cluster in the metropolitan area characterized by higher incidence rates.
Conclusions:The findings show a high number of vaccinated individuals among cases, which suggest an incomplete vaccination schedule, and children younger than one year old as more susceptible for hospitalization.
Keyword(s): Measles, Re-emergence, EpidemiologyCOI Other: The authors declare no conflict of interest
Session Type: 1,5-hour Oral Session
Session Title: 1,5-hour Oral Session
Authors(s): C. Makarenko (1), A. San Pedro (2), N. Paiva (1), R. Medronho (1), G. Gibson (1)
Authors Affiliations(s): (1) Instituto de Estudos em Saúde Coletiva, Universidade Federal do Rio de Janeiro -UFRJ, Brazil, (2) Grupo de Análise Territorial em Saúde - GATES, Brazil
Background:
Although it was declared as having been eliminated from the Americas in 2016, measles has again become a public health concern in several Latin American countries. In Brazil, the most populous state in the country, São Paulo State (SPS), faced a massive outbreak in 2019, that began with imported cases from Europe and Israel. This study aims to analyze the clinical-epidemiological profile of confirmed measles cases in SPS and analyze spatial and temporal distribution during the 2019 epidemic.
Methods:A cross-sectional study was carried out based on confirmed measles cases in SPS. The cases were described according to socioeconomic, epidemiological, and clinical variables and stratified by vaccination status and hospitalization. Incidence rates per municipality were stabilized by Local Empirical Bayes methods before mapping.
Results:There were 15,607 confirmed cases of measles in SPS in 2019, of which 2,039 were hospitalized and 17 resulted in death. After the first confirmed case on Epidemiological Week (EW) 6, the epidemic peak was reached on EW 33, when 1,446 cases were confirmed. Most cases were men (52.1%), between 18 and 29 years old (39.7%). Among those who were 18 and older, the majority had at least 9 years of formal schooling (56.1%). Around 70.0% have self-declared as being white. The main clinical manifestation, beside fever and rash, were cough (76.1%), coryza (62.7%) and conjunctivitis (33.0%). On a bivariate analysis, we observed higher prevalence of vaccination in the group younger than 29 years of age. Self-declared black and brown patients had a lower vaccination prevalence in comparison with white patients (PR= 0.83; CI95%=0.74,0.95; PR=0.83, CI95%=0.79,0.87). Similarly, we observed lower prevalences of vaccination in groups with less years of schooling when compared to those with 13 years or more (PR = 0.72, 95% CI95% = 0.63,0.82). Regarding hospitalization, children younger than 1 year old had a higher prevalence compared to older age groups. Spatial analysis showed a main cluster in the metropolitan area characterized by higher incidence rates.
Conclusions:The findings show a high number of vaccinated individuals among cases, which suggest an incomplete vaccination schedule, and children younger than one year old as more susceptible for hospitalization.
Keyword(s): Measles, Re-emergence, EpidemiologyCOI Other: The authors declare no conflict of interest