Session Type: ePosters
Session Title: ePosters
Authors(s): N.T.Q. Nguyen (1), H.Q. Nguyen (1), Y. Hsia (2), J. Bielicki (3), M. Sharland (3)
Authors Affiliations(s): (1) Faculty of Pharmacy, University of Medicine and Pharmacy at Ho Chi Minh City, Vietnam, Vietnam, (2) School of Pharmacy, Queen’s University Belfast, UK, United Kingdom, (3) Paediatric Infectious Diseases Research Group, Institute for Infection and Immunity, St George’s University, London, UK, United Kingdom
Background:
Daily Defined Doses are complex measures of antibiotic use and do not engage prescribers. Novel ways of presenting data may assist with policy interventions. We explored the feasibility of using “Standard Courses” of antibiotics (SCs) as a proxy of relative patterns of AWaRe antibiotic use in LMICs and HICs to produce estimates of variation in population rates of prescribing.
Methods:One-year (2015) wholesale antibiotic data from 75 countries from IQVIA MIDAS was used. Antibiotic consumption was measured in standard units (SU) with 1 SU a single ampoule/ vial, single tablet, capsule or 5ml oral suspension. We used international prescribing guidelines to determine the average number of SUs that represent a Standard Course (15 SU for oral – three times daily dosing for 5 days; 21 SU for parenteral – three times daily dosing for 7 days). We estimated consumption in SCs, standardised for 2015 World Bank country population. Antibiotics were classified by 2019 WHO EML AWaRe into Access, Watch and Reserve and countries by World Bank income.
Results:Total antibiotic consumption across 39 HICs and 36 LMICs were 21 and 55 billion SUs (1.4 and 3.6 billion SCs). The median number of SCs/1,000 inhabitants for Access, Watch, and Reserve oral antibiotics were 589 (IQR: 475-765), 268 (160-349), 0.13 (0.02-0.35) for HICs, and 518 (333-789), 184 (116-292), and 0.02 (0.001-0.13) for LMICs, respectively. Compared to the median, the highest HIC rates of Access prescribing were in New Zealand (2.3 times), and for Watch, Japan (3.3 times). For LMICs the highest Access use was in Tunisia (2.7 times), and for Watch use was Turkey (3.8 times). For parenteral formulations, the median number of SCs/1,000 inhabitants for Access, Watch, and Reserve group were 17.7 (IQR: 7.8-23.9), 19.0 (10.9-27.1), 0.52 (0.14-1.14) for HICs, and 8.5 (2.0-20.6), 6.9 (2.2-26.4), 0.03 (0.003-0.19) for LMICs, respectively.
Conclusions:Novel methods of presenting comparative data that can more easily be recognised by prescribers could be useful for policy engagement, with clear recognition of the data limitations. Wide variations in Standard Courses of antibiotic use between countries are seen for both HIC and LMICs.
Keyword(s): AWaRe system, standardised course, antibiotic consumptionSession Type: ePosters
Session Title: ePosters
Authors(s): N.T.Q. Nguyen (1), H.Q. Nguyen (1), Y. Hsia (2), J. Bielicki (3), M. Sharland (3)
Authors Affiliations(s): (1) Faculty of Pharmacy, University of Medicine and Pharmacy at Ho Chi Minh City, Vietnam, Vietnam, (2) School of Pharmacy, Queen’s University Belfast, UK, United Kingdom, (3) Paediatric Infectious Diseases Research Group, Institute for Infection and Immunity, St George’s University, London, UK, United Kingdom
Background:
Daily Defined Doses are complex measures of antibiotic use and do not engage prescribers. Novel ways of presenting data may assist with policy interventions. We explored the feasibility of using “Standard Courses” of antibiotics (SCs) as a proxy of relative patterns of AWaRe antibiotic use in LMICs and HICs to produce estimates of variation in population rates of prescribing.
Methods:One-year (2015) wholesale antibiotic data from 75 countries from IQVIA MIDAS was used. Antibiotic consumption was measured in standard units (SU) with 1 SU a single ampoule/ vial, single tablet, capsule or 5ml oral suspension. We used international prescribing guidelines to determine the average number of SUs that represent a Standard Course (15 SU for oral – three times daily dosing for 5 days; 21 SU for parenteral – three times daily dosing for 7 days). We estimated consumption in SCs, standardised for 2015 World Bank country population. Antibiotics were classified by 2019 WHO EML AWaRe into Access, Watch and Reserve and countries by World Bank income.
Results:Total antibiotic consumption across 39 HICs and 36 LMICs were 21 and 55 billion SUs (1.4 and 3.6 billion SCs). The median number of SCs/1,000 inhabitants for Access, Watch, and Reserve oral antibiotics were 589 (IQR: 475-765), 268 (160-349), 0.13 (0.02-0.35) for HICs, and 518 (333-789), 184 (116-292), and 0.02 (0.001-0.13) for LMICs, respectively. Compared to the median, the highest HIC rates of Access prescribing were in New Zealand (2.3 times), and for Watch, Japan (3.3 times). For LMICs the highest Access use was in Tunisia (2.7 times), and for Watch use was Turkey (3.8 times). For parenteral formulations, the median number of SCs/1,000 inhabitants for Access, Watch, and Reserve group were 17.7 (IQR: 7.8-23.9), 19.0 (10.9-27.1), 0.52 (0.14-1.14) for HICs, and 8.5 (2.0-20.6), 6.9 (2.2-26.4), 0.03 (0.003-0.19) for LMICs, respectively.
Conclusions:Novel methods of presenting comparative data that can more easily be recognised by prescribers could be useful for policy engagement, with clear recognition of the data limitations. Wide variations in Standard Courses of antibiotic use between countries are seen for both HIC and LMICs.
Keyword(s): AWaRe system, standardised course, antibiotic consumption
University of Medicine and Pharmacy at Ho Chi Minh City
Session Type: ePosters
Session Title: ePosters
Authors(s): N.T.Q. Nguyen (1), H.Q. Nguyen (1), Y. Hsia (2), J. Bielicki (3), M. Sharland (3)
Authors Affiliations(s): (1) Faculty of Pharmacy, University of Medicine and Pharmacy at Ho Chi Minh City, Vietnam, Vietnam, (2) School of Pharmacy, Queen’s University Belfast, UK, United Kingdom, (3) Paediatric Infectious Diseases Research Group, Institute for Infection and Immunity, St George’s University, London, UK, United Kingdom
Background:
Daily Defined Doses are complex measures of antibiotic use and do not engage prescribers. Novel ways of presenting data may assist with policy interventions. We explored the feasibility of using “Standard Courses” of antibiotics (SCs) as a proxy of relative patterns of AWaRe antibiotic use in LMICs and HICs to produce estimates of variation in population rates of prescribing.
Methods:One-year (2015) wholesale antibiotic data from 75 countries from IQVIA MIDAS was used. Antibiotic consumption was measured in standard units (SU) with 1 SU a single ampoule/ vial, single tablet, capsule or 5ml oral suspension. We used international prescribing guidelines to determine the average number of SUs that represent a Standard Course (15 SU for oral – three times daily dosing for 5 days; 21 SU for parenteral – three times daily dosing for 7 days). We estimated consumption in SCs, standardised for 2015 World Bank country population. Antibiotics were classified by 2019 WHO EML AWaRe into Access, Watch and Reserve and countries by World Bank income.
Results:Total antibiotic consumption across 39 HICs and 36 LMICs were 21 and 55 billion SUs (1.4 and 3.6 billion SCs). The median number of SCs/1,000 inhabitants for Access, Watch, and Reserve oral antibiotics were 589 (IQR: 475-765), 268 (160-349), 0.13 (0.02-0.35) for HICs, and 518 (333-789), 184 (116-292), and 0.02 (0.001-0.13) for LMICs, respectively. Compared to the median, the highest HIC rates of Access prescribing were in New Zealand (2.3 times), and for Watch, Japan (3.3 times). For LMICs the highest Access use was in Tunisia (2.7 times), and for Watch use was Turkey (3.8 times). For parenteral formulations, the median number of SCs/1,000 inhabitants for Access, Watch, and Reserve group were 17.7 (IQR: 7.8-23.9), 19.0 (10.9-27.1), 0.52 (0.14-1.14) for HICs, and 8.5 (2.0-20.6), 6.9 (2.2-26.4), 0.03 (0.003-0.19) for LMICs, respectively.
Conclusions:Novel methods of presenting comparative data that can more easily be recognised by prescribers could be useful for policy engagement, with clear recognition of the data limitations. Wide variations in Standard Courses of antibiotic use between countries are seen for both HIC and LMICs.
Keyword(s): AWaRe system, standardised course, antibiotic consumptionSession Type: ePosters
Session Title: ePosters
Authors(s): N.T.Q. Nguyen (1), H.Q. Nguyen (1), Y. Hsia (2), J. Bielicki (3), M. Sharland (3)
Authors Affiliations(s): (1) Faculty of Pharmacy, University of Medicine and Pharmacy at Ho Chi Minh City, Vietnam, Vietnam, (2) School of Pharmacy, Queen’s University Belfast, UK, United Kingdom, (3) Paediatric Infectious Diseases Research Group, Institute for Infection and Immunity, St George’s University, London, UK, United Kingdom
Background:
Daily Defined Doses are complex measures of antibiotic use and do not engage prescribers. Novel ways of presenting data may assist with policy interventions. We explored the feasibility of using “Standard Courses” of antibiotics (SCs) as a proxy of relative patterns of AWaRe antibiotic use in LMICs and HICs to produce estimates of variation in population rates of prescribing.
Methods:One-year (2015) wholesale antibiotic data from 75 countries from IQVIA MIDAS was used. Antibiotic consumption was measured in standard units (SU) with 1 SU a single ampoule/ vial, single tablet, capsule or 5ml oral suspension. We used international prescribing guidelines to determine the average number of SUs that represent a Standard Course (15 SU for oral – three times daily dosing for 5 days; 21 SU for parenteral – three times daily dosing for 7 days). We estimated consumption in SCs, standardised for 2015 World Bank country population. Antibiotics were classified by 2019 WHO EML AWaRe into Access, Watch and Reserve and countries by World Bank income.
Results:Total antibiotic consumption across 39 HICs and 36 LMICs were 21 and 55 billion SUs (1.4 and 3.6 billion SCs). The median number of SCs/1,000 inhabitants for Access, Watch, and Reserve oral antibiotics were 589 (IQR: 475-765), 268 (160-349), 0.13 (0.02-0.35) for HICs, and 518 (333-789), 184 (116-292), and 0.02 (0.001-0.13) for LMICs, respectively. Compared to the median, the highest HIC rates of Access prescribing were in New Zealand (2.3 times), and for Watch, Japan (3.3 times). For LMICs the highest Access use was in Tunisia (2.7 times), and for Watch use was Turkey (3.8 times). For parenteral formulations, the median number of SCs/1,000 inhabitants for Access, Watch, and Reserve group were 17.7 (IQR: 7.8-23.9), 19.0 (10.9-27.1), 0.52 (0.14-1.14) for HICs, and 8.5 (2.0-20.6), 6.9 (2.2-26.4), 0.03 (0.003-0.19) for LMICs, respectively.
Conclusions:Novel methods of presenting comparative data that can more easily be recognised by prescribers could be useful for policy engagement, with clear recognition of the data limitations. Wide variations in Standard Courses of antibiotic use between countries are seen for both HIC and LMICs.
Keyword(s): AWaRe system, standardised course, antibiotic consumption