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Abstract
Discussion Forum (0)
Abstract number: 2452

Session Type: ePosters

Session Title: ePosters

Authors(s): I. Gonçalves, C. Silva, S. Neves, S. Xará

Authors Affiliations(s): Centro Hospitalar Universitário do Porto, Portugal

Background:

Malaria is still responsible for a high level of morbidity and mortality throughout the world. Severe forms of the disease are mostly caused by P. falciparum and may lead to multiorgan dysfunction. Through unknown mechanisms, adults living in malaria endemic areas acquire a certain level of immunity by repeated exposure to the parasite and may be in some extent protected from having severe forms of the disease.

 

Case:

55-year-old portuguese man, who travels almost monthly to the Ivory Coast for professional reasons, where he stays for 10-15 days. He  does not routinely take malaria chemoprophylaxis or other measures to avoid mosquito bites.

He presented to the hospital 8 days after his arrival from the Ivory Coast with a febrile illness (max. 39ºC), headache and rhinorrhea. A clinical suspicion of COVID-19 was raised, and he was discharged with symptom-relieve measures. He returned after two days with persistent higher fever, diarrhea and confusion. He was diagnosed with malaria, with a positive blood smear showing a parasitemia of 25%, suggestive of P. falciparum. The patient presented multiorgan dysfunction with cardiovascular, respiratory, renal, hepatic, hematologic and metabolic dysfunctions. Prompt treatment with intravenous quinine plus doxycycline was started and he was admitted to the ICU. He presented a slow but favorable evolution, with a negative blood smear for Plasmodium on the fifth day. He had a full recovery from the multiple organ disfunctions.

Discussion:

Almost all malaria cases in Portugal are imported by travelers, usually from African countries. Severe malaria is a serious condition that if untreated is almost invariably fatal. It is important that clinicians always remember to rule out malaria when evaluating febrile patients coming from malaria endemic areas.

The delay on appropriate diagnosis on the above-mentioned case, part of which related to the COVID-19 pandemic, could have led to unrecoverable morbidity or even the death of the patient. We believe he had a certain level of acquired immunity, owing to the repeated periods he lived in the African country, which contributed to the favorable outcome.

Keyword(s): Malaria, Travel health, Plasmodium falciparum

Abstract number: 2452

Session Type: ePosters

Session Title: ePosters

Authors(s): I. Gonçalves, C. Silva, S. Neves, S. Xará

Authors Affiliations(s): Centro Hospitalar Universitário do Porto, Portugal

Background:

Malaria is still responsible for a high level of morbidity and mortality throughout the world. Severe forms of the disease are mostly caused by P. falciparum and may lead to multiorgan dysfunction. Through unknown mechanisms, adults living in malaria endemic areas acquire a certain level of immunity by repeated exposure to the parasite and may be in some extent protected from having severe forms of the disease.

 

Case:

55-year-old portuguese man, who travels almost monthly to the Ivory Coast for professional reasons, where he stays for 10-15 days. He  does not routinely take malaria chemoprophylaxis or other measures to avoid mosquito bites.

He presented to the hospital 8 days after his arrival from the Ivory Coast with a febrile illness (max. 39ºC), headache and rhinorrhea. A clinical suspicion of COVID-19 was raised, and he was discharged with symptom-relieve measures. He returned after two days with persistent higher fever, diarrhea and confusion. He was diagnosed with malaria, with a positive blood smear showing a parasitemia of 25%, suggestive of P. falciparum. The patient presented multiorgan dysfunction with cardiovascular, respiratory, renal, hepatic, hematologic and metabolic dysfunctions. Prompt treatment with intravenous quinine plus doxycycline was started and he was admitted to the ICU. He presented a slow but favorable evolution, with a negative blood smear for Plasmodium on the fifth day. He had a full recovery from the multiple organ disfunctions.

Discussion:

Almost all malaria cases in Portugal are imported by travelers, usually from African countries. Severe malaria is a serious condition that if untreated is almost invariably fatal. It is important that clinicians always remember to rule out malaria when evaluating febrile patients coming from malaria endemic areas.

The delay on appropriate diagnosis on the above-mentioned case, part of which related to the COVID-19 pandemic, could have led to unrecoverable morbidity or even the death of the patient. We believe he had a certain level of acquired immunity, owing to the repeated periods he lived in the African country, which contributed to the favorable outcome.

Keyword(s): Malaria, Travel health, Plasmodium falciparum

Not all is COVID-19: a case of severe imported malaria
Dra Inês Gonçalves
Dra Inês Gonçalves
ESCMID eAcademy. Gonçalves I. 07/09/2021; 328750; 2452
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Dra Inês Gonçalves
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Abstract
Discussion Forum (0)
Abstract number: 2452

Session Type: ePosters

Session Title: ePosters

Authors(s): I. Gonçalves, C. Silva, S. Neves, S. Xará

Authors Affiliations(s): Centro Hospitalar Universitário do Porto, Portugal

Background:

Malaria is still responsible for a high level of morbidity and mortality throughout the world. Severe forms of the disease are mostly caused by P. falciparum and may lead to multiorgan dysfunction. Through unknown mechanisms, adults living in malaria endemic areas acquire a certain level of immunity by repeated exposure to the parasite and may be in some extent protected from having severe forms of the disease.

 

Case:

55-year-old portuguese man, who travels almost monthly to the Ivory Coast for professional reasons, where he stays for 10-15 days. He  does not routinely take malaria chemoprophylaxis or other measures to avoid mosquito bites.

He presented to the hospital 8 days after his arrival from the Ivory Coast with a febrile illness (max. 39ºC), headache and rhinorrhea. A clinical suspicion of COVID-19 was raised, and he was discharged with symptom-relieve measures. He returned after two days with persistent higher fever, diarrhea and confusion. He was diagnosed with malaria, with a positive blood smear showing a parasitemia of 25%, suggestive of P. falciparum. The patient presented multiorgan dysfunction with cardiovascular, respiratory, renal, hepatic, hematologic and metabolic dysfunctions. Prompt treatment with intravenous quinine plus doxycycline was started and he was admitted to the ICU. He presented a slow but favorable evolution, with a negative blood smear for Plasmodium on the fifth day. He had a full recovery from the multiple organ disfunctions.

Discussion:

Almost all malaria cases in Portugal are imported by travelers, usually from African countries. Severe malaria is a serious condition that if untreated is almost invariably fatal. It is important that clinicians always remember to rule out malaria when evaluating febrile patients coming from malaria endemic areas.

The delay on appropriate diagnosis on the above-mentioned case, part of which related to the COVID-19 pandemic, could have led to unrecoverable morbidity or even the death of the patient. We believe he had a certain level of acquired immunity, owing to the repeated periods he lived in the African country, which contributed to the favorable outcome.

Keyword(s): Malaria, Travel health, Plasmodium falciparum

Abstract number: 2452

Session Type: ePosters

Session Title: ePosters

Authors(s): I. Gonçalves, C. Silva, S. Neves, S. Xará

Authors Affiliations(s): Centro Hospitalar Universitário do Porto, Portugal

Background:

Malaria is still responsible for a high level of morbidity and mortality throughout the world. Severe forms of the disease are mostly caused by P. falciparum and may lead to multiorgan dysfunction. Through unknown mechanisms, adults living in malaria endemic areas acquire a certain level of immunity by repeated exposure to the parasite and may be in some extent protected from having severe forms of the disease.

 

Case:

55-year-old portuguese man, who travels almost monthly to the Ivory Coast for professional reasons, where he stays for 10-15 days. He  does not routinely take malaria chemoprophylaxis or other measures to avoid mosquito bites.

He presented to the hospital 8 days after his arrival from the Ivory Coast with a febrile illness (max. 39ºC), headache and rhinorrhea. A clinical suspicion of COVID-19 was raised, and he was discharged with symptom-relieve measures. He returned after two days with persistent higher fever, diarrhea and confusion. He was diagnosed with malaria, with a positive blood smear showing a parasitemia of 25%, suggestive of P. falciparum. The patient presented multiorgan dysfunction with cardiovascular, respiratory, renal, hepatic, hematologic and metabolic dysfunctions. Prompt treatment with intravenous quinine plus doxycycline was started and he was admitted to the ICU. He presented a slow but favorable evolution, with a negative blood smear for Plasmodium on the fifth day. He had a full recovery from the multiple organ disfunctions.

Discussion:

Almost all malaria cases in Portugal are imported by travelers, usually from African countries. Severe malaria is a serious condition that if untreated is almost invariably fatal. It is important that clinicians always remember to rule out malaria when evaluating febrile patients coming from malaria endemic areas.

The delay on appropriate diagnosis on the above-mentioned case, part of which related to the COVID-19 pandemic, could have led to unrecoverable morbidity or even the death of the patient. We believe he had a certain level of acquired immunity, owing to the repeated periods he lived in the African country, which contributed to the favorable outcome.

Keyword(s): Malaria, Travel health, Plasmodium falciparum

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