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Abstract
Discussion Forum (0)
Abstract number: 488

Session Type: ePosters

Session Title: ePosters

Authors(s): M. Bourgeois (1), B. Delaere (1), N. Ausselet (1), E. Dupont (1), M. Berghmans (1), J. Flament (2), H. Thonon (2), I. Michaux (3), G. Horlait (3), T.D. Huang (4), P. Bogaerts (4), C. Laurent (5), C. Vastrade (5), O. Denis (4)

Authors Affiliations(s): (1) CHU UCL Namur, Infectious Diseases Dpt, Belgium, (2) CHU UCL Namur, Emergency Dpt, Belgium, (3) CHU UCL Namur, Intensive Care Dpt, Belgium, (4) CHU UCL Namur, Laboratory of Microbiology, Belgium, (5) CHU UCL Namur, Infection Control Unit, Belgium

Background:

FLU/RSV adult hospitalizations are subject to a systematic epidemiological surveillance process performed at CHU UCL Namur (member of the Belgian Sentinel Hospital Network for severe influenza monitoring).  A similar protocol has been implemented in the context of the SARS-CoV-2 pandemic outbreak.  We aim to compare the epidemiological, clinical and outcome data in our hospitalized population during four FLU/RSV seasons (2015-2019) to those of two consecutive COVID-19 epidemic waves (2020 and early 2021).

 

Methods:

This study was conducted in a 440-beds tertiary hospital.  Surveillance timelines were defined according to epidemiological criteria related to the circulation of FLU/RSV (2015-2019) and SARS-CoV2 (2020-2021) viruses in the population.  Adult patients matching with a Severe Acute Respiratory Infection (SARI) case definition at the Emergency Department (ED) were tested by RT-PCR assays targeting FLU/RSV or SARS-CoV-2 viruses.  Epidemiological, clinical and outcome data were retrospectively reviewed to assess the specificities of FLU/RSV and COVID-19 infections.

Results:

A FLU or RSV virus was documented in 316 SARI patients (2015-2019; 4 consecutive winter seasons) and a SARS-COV-2 virus in 392 (2020-2021 epidemic waves).  COVID-19 patients were more likely to need Intensive Care Unit (ICU) admission (24% vs 17%; 96/392 vs 54/316), had a higher ICU length of stay (18 days/median vs 6 for patients alive at discharge), and were younger (61 years/median vs 68 in ICU patients alive at discharge; 66 years/median vs 75 in ICU patients that died).  Globally, COVID-19 patients were more likely to die from their infection (21% vs 6%; 83/392 vs 20/316), and death casualties were higher on wards than in ICU (53/82 vs 9/20; 82 years/median vs 78).  Despite higher morbidity and mortality, patients hospitalized with a SARS-COV-2 infection were less susceptible than FLU/RSV patients to present comorbidities such as pulmonary disease (23% vs 47%; 92/392 vs 150/316), hematological malignancy (7% vs 19%; 27/392 vs 60/316) and immunosuppression (6% vs 16%; 25/392 vs 52/316).

Conclusions:

Adult COVID-19 hospitalization patterns were significantly more severe compared to FLU/RSV in terms of hospital and ICU admissions, ICU length of stay, ICU and ward mortality rates.

Keyword(s): COVID-19, FLU/RSV, Epidemiology, Adult hospitalization

Abstract number: 488

Session Type: ePosters

Session Title: ePosters

Authors(s): M. Bourgeois (1), B. Delaere (1), N. Ausselet (1), E. Dupont (1), M. Berghmans (1), J. Flament (2), H. Thonon (2), I. Michaux (3), G. Horlait (3), T.D. Huang (4), P. Bogaerts (4), C. Laurent (5), C. Vastrade (5), O. Denis (4)

Authors Affiliations(s): (1) CHU UCL Namur, Infectious Diseases Dpt, Belgium, (2) CHU UCL Namur, Emergency Dpt, Belgium, (3) CHU UCL Namur, Intensive Care Dpt, Belgium, (4) CHU UCL Namur, Laboratory of Microbiology, Belgium, (5) CHU UCL Namur, Infection Control Unit, Belgium

Background:

FLU/RSV adult hospitalizations are subject to a systematic epidemiological surveillance process performed at CHU UCL Namur (member of the Belgian Sentinel Hospital Network for severe influenza monitoring).  A similar protocol has been implemented in the context of the SARS-CoV-2 pandemic outbreak.  We aim to compare the epidemiological, clinical and outcome data in our hospitalized population during four FLU/RSV seasons (2015-2019) to those of two consecutive COVID-19 epidemic waves (2020 and early 2021).

 

Methods:

This study was conducted in a 440-beds tertiary hospital.  Surveillance timelines were defined according to epidemiological criteria related to the circulation of FLU/RSV (2015-2019) and SARS-CoV2 (2020-2021) viruses in the population.  Adult patients matching with a Severe Acute Respiratory Infection (SARI) case definition at the Emergency Department (ED) were tested by RT-PCR assays targeting FLU/RSV or SARS-CoV-2 viruses.  Epidemiological, clinical and outcome data were retrospectively reviewed to assess the specificities of FLU/RSV and COVID-19 infections.

Results:

A FLU or RSV virus was documented in 316 SARI patients (2015-2019; 4 consecutive winter seasons) and a SARS-COV-2 virus in 392 (2020-2021 epidemic waves).  COVID-19 patients were more likely to need Intensive Care Unit (ICU) admission (24% vs 17%; 96/392 vs 54/316), had a higher ICU length of stay (18 days/median vs 6 for patients alive at discharge), and were younger (61 years/median vs 68 in ICU patients alive at discharge; 66 years/median vs 75 in ICU patients that died).  Globally, COVID-19 patients were more likely to die from their infection (21% vs 6%; 83/392 vs 20/316), and death casualties were higher on wards than in ICU (53/82 vs 9/20; 82 years/median vs 78).  Despite higher morbidity and mortality, patients hospitalized with a SARS-COV-2 infection were less susceptible than FLU/RSV patients to present comorbidities such as pulmonary disease (23% vs 47%; 92/392 vs 150/316), hematological malignancy (7% vs 19%; 27/392 vs 60/316) and immunosuppression (6% vs 16%; 25/392 vs 52/316).

Conclusions:

Adult COVID-19 hospitalization patterns were significantly more severe compared to FLU/RSV in terms of hospital and ICU admissions, ICU length of stay, ICU and ward mortality rates.

Keyword(s): COVID-19, FLU/RSV, Epidemiology, Adult hospitalization

COVID-19 and flu/respiratory syncytial virus (RSV) adult hospitalisations in a Belgian tertiary referral centre: epidemiological, clinical and outcome data comparison
Marc Bourgeois
Marc Bourgeois
Affiliations:
CHU UCL Namur (Yvoir, Belgium)
ESCMID eAcademy. Bourgeois M. 07/09/2021; 327622; 488;
user
Marc Bourgeois
Affiliations:
CHU UCL Namur (Yvoir, Belgium)
Abstract
Discussion Forum (0)
Abstract number: 488

Session Type: ePosters

Session Title: ePosters

Authors(s): M. Bourgeois (1), B. Delaere (1), N. Ausselet (1), E. Dupont (1), M. Berghmans (1), J. Flament (2), H. Thonon (2), I. Michaux (3), G. Horlait (3), T.D. Huang (4), P. Bogaerts (4), C. Laurent (5), C. Vastrade (5), O. Denis (4)

Authors Affiliations(s): (1) CHU UCL Namur, Infectious Diseases Dpt, Belgium, (2) CHU UCL Namur, Emergency Dpt, Belgium, (3) CHU UCL Namur, Intensive Care Dpt, Belgium, (4) CHU UCL Namur, Laboratory of Microbiology, Belgium, (5) CHU UCL Namur, Infection Control Unit, Belgium

Background:

FLU/RSV adult hospitalizations are subject to a systematic epidemiological surveillance process performed at CHU UCL Namur (member of the Belgian Sentinel Hospital Network for severe influenza monitoring).  A similar protocol has been implemented in the context of the SARS-CoV-2 pandemic outbreak.  We aim to compare the epidemiological, clinical and outcome data in our hospitalized population during four FLU/RSV seasons (2015-2019) to those of two consecutive COVID-19 epidemic waves (2020 and early 2021).

 

Methods:

This study was conducted in a 440-beds tertiary hospital.  Surveillance timelines were defined according to epidemiological criteria related to the circulation of FLU/RSV (2015-2019) and SARS-CoV2 (2020-2021) viruses in the population.  Adult patients matching with a Severe Acute Respiratory Infection (SARI) case definition at the Emergency Department (ED) were tested by RT-PCR assays targeting FLU/RSV or SARS-CoV-2 viruses.  Epidemiological, clinical and outcome data were retrospectively reviewed to assess the specificities of FLU/RSV and COVID-19 infections.

Results:

A FLU or RSV virus was documented in 316 SARI patients (2015-2019; 4 consecutive winter seasons) and a SARS-COV-2 virus in 392 (2020-2021 epidemic waves).  COVID-19 patients were more likely to need Intensive Care Unit (ICU) admission (24% vs 17%; 96/392 vs 54/316), had a higher ICU length of stay (18 days/median vs 6 for patients alive at discharge), and were younger (61 years/median vs 68 in ICU patients alive at discharge; 66 years/median vs 75 in ICU patients that died).  Globally, COVID-19 patients were more likely to die from their infection (21% vs 6%; 83/392 vs 20/316), and death casualties were higher on wards than in ICU (53/82 vs 9/20; 82 years/median vs 78).  Despite higher morbidity and mortality, patients hospitalized with a SARS-COV-2 infection were less susceptible than FLU/RSV patients to present comorbidities such as pulmonary disease (23% vs 47%; 92/392 vs 150/316), hematological malignancy (7% vs 19%; 27/392 vs 60/316) and immunosuppression (6% vs 16%; 25/392 vs 52/316).

Conclusions:

Adult COVID-19 hospitalization patterns were significantly more severe compared to FLU/RSV in terms of hospital and ICU admissions, ICU length of stay, ICU and ward mortality rates.

Keyword(s): COVID-19, FLU/RSV, Epidemiology, Adult hospitalization

Abstract number: 488

Session Type: ePosters

Session Title: ePosters

Authors(s): M. Bourgeois (1), B. Delaere (1), N. Ausselet (1), E. Dupont (1), M. Berghmans (1), J. Flament (2), H. Thonon (2), I. Michaux (3), G. Horlait (3), T.D. Huang (4), P. Bogaerts (4), C. Laurent (5), C. Vastrade (5), O. Denis (4)

Authors Affiliations(s): (1) CHU UCL Namur, Infectious Diseases Dpt, Belgium, (2) CHU UCL Namur, Emergency Dpt, Belgium, (3) CHU UCL Namur, Intensive Care Dpt, Belgium, (4) CHU UCL Namur, Laboratory of Microbiology, Belgium, (5) CHU UCL Namur, Infection Control Unit, Belgium

Background:

FLU/RSV adult hospitalizations are subject to a systematic epidemiological surveillance process performed at CHU UCL Namur (member of the Belgian Sentinel Hospital Network for severe influenza monitoring).  A similar protocol has been implemented in the context of the SARS-CoV-2 pandemic outbreak.  We aim to compare the epidemiological, clinical and outcome data in our hospitalized population during four FLU/RSV seasons (2015-2019) to those of two consecutive COVID-19 epidemic waves (2020 and early 2021).

 

Methods:

This study was conducted in a 440-beds tertiary hospital.  Surveillance timelines were defined according to epidemiological criteria related to the circulation of FLU/RSV (2015-2019) and SARS-CoV2 (2020-2021) viruses in the population.  Adult patients matching with a Severe Acute Respiratory Infection (SARI) case definition at the Emergency Department (ED) were tested by RT-PCR assays targeting FLU/RSV or SARS-CoV-2 viruses.  Epidemiological, clinical and outcome data were retrospectively reviewed to assess the specificities of FLU/RSV and COVID-19 infections.

Results:

A FLU or RSV virus was documented in 316 SARI patients (2015-2019; 4 consecutive winter seasons) and a SARS-COV-2 virus in 392 (2020-2021 epidemic waves).  COVID-19 patients were more likely to need Intensive Care Unit (ICU) admission (24% vs 17%; 96/392 vs 54/316), had a higher ICU length of stay (18 days/median vs 6 for patients alive at discharge), and were younger (61 years/median vs 68 in ICU patients alive at discharge; 66 years/median vs 75 in ICU patients that died).  Globally, COVID-19 patients were more likely to die from their infection (21% vs 6%; 83/392 vs 20/316), and death casualties were higher on wards than in ICU (53/82 vs 9/20; 82 years/median vs 78).  Despite higher morbidity and mortality, patients hospitalized with a SARS-COV-2 infection were less susceptible than FLU/RSV patients to present comorbidities such as pulmonary disease (23% vs 47%; 92/392 vs 150/316), hematological malignancy (7% vs 19%; 27/392 vs 60/316) and immunosuppression (6% vs 16%; 25/392 vs 52/316).

Conclusions:

Adult COVID-19 hospitalization patterns were significantly more severe compared to FLU/RSV in terms of hospital and ICU admissions, ICU length of stay, ICU and ward mortality rates.

Keyword(s): COVID-19, FLU/RSV, Epidemiology, Adult hospitalization

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